2010

Berger R, Fiegl H, Goebel G, Obexer P, Ausserlechner M, Doppler W, Hauser-Kronberger C, Reitsamer R, Egle D, Reimer D, Müller-Holzner E, Jones A, Widschwendter M: Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors. Cancer Sci 2010, 101:1059-1066 PMID: 20156214.

Domokos M, Jakus J, Szeker K, Csizinszky R, Csiko G, Neogrady Z, Csordas A, Galfi P: Butyrate-induced cell death and differentiation are associated with distinct patterns of ROS in HT29-derived human colon cancer cells. Dig. Dis. Sci 2010, 55:920-930 PMID: 19434493.

Garczarczyk D, Szeker K, Galfi P, Csordas A, Hofmann J: Protein kinase Cgamma in colon cancer cells: expression, Thr514 phosphorylation and sensitivity to butyrate-mediated upregulation as related to the degree of differentiation. Chem. Biol. Interact 2010, 185:25-32 PMID: 20188713.

Grespi F, Soratroi C, Krumschnabel G, Sohm B, Ploner C, Geley S, Hengst L, Häcker G, Villunger A: BH3-only protein Bmf mediates apoptosis upon inhibition of CAP-dependent protein synthesis. Cell Death Differ 2010, 17:1672-1683 PMID: 20706276.

Kravchenko O, Mitroshin I, Nikonov S, Piendl W, Garber M: Structure of a two-domain N-terminal fragment of ribosomal protein L10 from Methanococcus jannaschii reveals a specific piece of the archaeal ribosomal stalk. J. Mol. Biol 2010, 399:214-220 PMID: 20399793.

Maier E, Kurz K, Jenny M, Schennach H, Ueberall F, Fuchs D: Food preservatives sodium benzoate and propionic acid and colorant curcumin suppress Th1-type immune response in vitro. Food Chem. Toxicol 2010, 48:1950-1956 PMID: 20435078.

Mühlmann G, Untergasser G, Zitt M, Zitt M, Maier H, Mikuz G, Kronberger IE, Haffner MC, Gunsilius E, Ofner D: Immunohistochemically detectable dickkopf-3 expression in tumor vessels predicts survival in gastric cancer. Virchows Arch 2010, 456:635-646 PMID: 20473620.

Nazarenko I, Jenny M, Keil J, Gieseler C, Weisshaupt K, Sehouli J, Legewie S, Herbst L, Weichert W, Darb-Esfahani S, Dietel M, Schäfer R, Ueberall F, Sers C: Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer. Mol. Cancer Res 2010, 8:919-934 PMID: 20501645.

Parajuli N, Müller-Holzner E, Böck G, Werner ER, Villunger A, Doppler W: Infiltrating CD11b+CD11c+ cells have the potential to mediate inducible nitric oxide synthase-dependent cell death in mammary carcinomas of HER-2/neu transgenic mice. Int. J. Cancer 2010, 126:896-908 PMID: 19653277.

Radford DJ, Wang K, McNelis JC, Taylor AE, Hechenberger G, Hofmann J, Chahal H, Arlt W, Lord JM: Dehdyroepiandrosterone sulfate directly activates protein kinase C-beta to increase human neutrophil superoxide generation. Mol. Endocrinol 2010, 24:813-821 PMID: 20172962.

Schroecksnadel S, Jenny M, Kurz K, Klein A, Ledochowski M, Uberall F, Fuchs D: LPS-induced NF-kappaB expression in THP-1Blue cells correlates with neopterin production and activity of indoleamine 2,3-dioxygenase. Biochem. Biophys. Res. Commun 2010, 399:642-646 PMID: 20691158.

Sucher R, Gehwolf P, Oberhuber R, Hermann M, Margreiter C, Werner ER, Obrist P, Schneeberger S, Ollinger R, Margreiter R, Brandacher G: Tetrahydrobiopterin protects the kidney from ischemia-reperfusion injury. Kidney Int 2010, 77:681-689 PMID: 20164829.

Sucher, G.,: Indoleamine 2,3-Dioxygenase (IDO) and Treg Support Are Critical for CTLA4Ig Mediated Tolerance Induction to Solid Organ Allografts. American Journal of Transplantation 2010:P. 206-206.

2009

Berlato C, Doppler W: Selective response to insulin versus insulin-like growth factor-I and -II and up-regulation of insulin receptor splice variant B in the differentiated mouse mammary epithelium. Endocrinology 2009, 150:2924-2933 PMID: 19246539.

Ecker K, Hengst L: Skp2: caught in the Akt. Nat. Cell Biol 2009, 11:377-379 PMID: 19337320.

Garczarczyk D, Toton E, Biedermann V, Rosivatz E, Rechfeld F, Rybczynska M, Hofmann J: Signal transduction of constitutively active protein kinase C epsilon. Cell. Signal 2009, 21:745-752 PMID: 19168130.

Grunicke HH: Coordinated regulation of Ras-, Rac-, and Ca2+-dependent signaling pathways. Crit. Rev. Eukaryot. Gene Expr 2009, 19:139-169 PMID: 19392649.

Haffner MC, Kronberger IE, Ross JS, Sheehan CE, Zitt M, Mühlmann G, Ofner D, Zelger B, Ensinger C, Yang XJ, Geley S, Margreiter R, Bander NH: Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers. Hum. Pathol 2009, 40:1754-1761 PMID: 19716160.

Hoeller D, Dikic I: Targeting the ubiquitin system in cancer therapy. Nature 2009, 458:438-444 PMID: 19325623.

Hofmann J, Easmon J, Puerstinger G, Heinisch G, Jenny M, Shtil AA, Hermann M, Condorelli DF, Sciré S, Musumarra G: N-benzoxazol-2-yl-N’-1-(isoquinolin-3-yl-ethylidene)-hydrazine, a novel compound with antitumor activity, induces radicals and dissipation of mitochondrial membrane potential. Invest New Drugs 2009, 27:189-202 PMID: 18612590.

Jenny M, Santer E, Klein A, Ledochowski M, Schennach H, Ueberall F, Fuchs D: Cacao extracts suppress tryptophan degradation of mitogen-stimulated peripheral blood mononuclear cells. J Ethnopharmacol 2009, 122:261-267 PMID: 19330924.

Malinowska K, Cavarretta IT, Susani M, Wrulich OA, Uberall F, Kenner L, Culig Z: Identification of mu-crystallin as an androgen-regulated gene in human prostate cancer. Prostate 2009, 69:1109-1118 PMID: 19353593.

Neuwirt H, Puhr M, Santer FR, Susani M, Doppler W, Marcias G, Rauch V, Brugger M, Hobisch A, Kenner L, Culig Z: Suppressor of cytokine signaling (SOCS)-1 is expressed in human prostate cancer and exerts growth-inhibitory function through down-regulation of cyclins and cyclin-dependent kinases. Am. J. Pathol 2009, 174:1921-1930 PMID: 19342366.

Parajuli N, Doppler W: Precision-cut slice cultures of tumors from MMTV-neu mice for the study of the ex vivo response to cytokines and cytotoxic drugs. In Vitro Cell. Dev. Biol. Anim 2009, 45:442-450 PMID: 19533258.

Rothmeier AS, Ischenko I, Joore J, Garczarczyk D, Fürst R, Bruns CJ, Vollmar AM, Zahler S: Investigation of the marine compound spongistatin 1 links the inhibition of PKCalpha translocation to nonmitotic effects of tubulin antagonism in angiogenesis. FASEB J 2009, 23:1127-1137 PMID: 19056838.

Sucher, G.,: INDOLEAMINE 2,3-DIOXYGENASE (IDO) AND Treg SUPPORT ARE CRITICAL FOR CTLA4Ig MEDIATED TOLERANCE INDUCTION TO SOLID ORGAN ALLOGRAFTS. Transplant International 2009:P. 94-94.

Sucher, G.,: Tetrahydrobiopterin Offsets Microvascular Renal Ischemia Reperfusion Injury Via Sustainment of No Homeostasis. Transplant International 2009:P. 46-46.